Mother Brain

Mother Brain (マザーブレイン, Mazā Burein) is a recurring antagonist and boss in the Metroid series. She is a cold and ill-tempered AI created by the Chozo, but turned against them when the Space Pirates and Ridley invaded Zebes. Mother Brain saw potential in the pirates and decided that with them helping, she could bring true order to the universe by "resetting everything back to zero". Mother Brain was seen as the main antagonist in Metroid, Super Metroid, and Metroid: Zero Mission. She is also seen in a flashback during Metroid: Other M, and her consciousness was responsible for the events of that game as well. In the Japanese website for Zero Mission, she is given the title Mad Oversee

STRATAGY

Just fire missiles or super missiles whilst dodging the attacks that she and her cannons fire

TRIVIA
 * Since the Metroid series was inspired by the Alien movies as speculated, Mother Brain's name may have derived from the main computer of the Nostromo, "Mother".
 * In a PC World article, Mother Brain was voted as #6 of the top 47 "most diabolical videogame villains of all time."
 * Several sources in past media, along with Metroid: Other M's portrayal of MB's abilities, imply that Mother Brain can influence/control her forces and wildlife with telepathy. This may explain why a large portion of the native flora and fauna on Zebes are highly aggressive toward Samus, as the Pirate leader is directing them against her. The first mention of her psionic abilities in media appeared in the Nintendo Comic System story: The Coming of a Hero, in which she is shown to display mental control over the Metroids.
 * Samus states in Other M that Mother Brain's telepathy is the only thing that can control Metroids; however there is proof that she does not have complete dominance over them, making this method of control arguably far from perfect. Circumstantial evidence that supports this is the cutscene that plays in Zero Mission when Samus enters Tourian, which clearly show Metroids having broken free and killing all Pirate personnel despite being near Mother Brain; this may have happened once more in Super Metroid, explaining the presence of unrestrained Metroids in numerous rooms within the rebuilt Tourian. Despite no in-game evidence, if one considers Mother Brain's rather cold and malevolent disposition seen in other media, the Metroids might've been intentionally released at the Pirates' expense to eliminate Samus.